Background Enteroviruses, which may cause gastroenteritis or upper respiratory tract infections, are well-known to have neurotropism – a predilection in a proportion of individuals to spread to certain types of neurones, thereby resulting in characteristic neurological syndromes that occur after … Continue reading
Background Sporadic cerebral amyloid angiopathy (CAA) is the most common cause of lobar intracranial haemorrhage, which in itself accounts for about 5-10% of all strokes. Amyloid deposition in small arteries of the cerebrum leads to friability and haemorrhage. There are also … Continue reading
Background The accompanying primer, Thrombolysis for Stroke and role of CT perfusion Imaging, describes the difficulties and potential shortcomings of thrombolysis for acute stroke and the way that CT perfusion may improve patient selection for thrombolysis. This paper, by Hopyat … Continue reading
Stroke, defined as a sudden vascular event resulting in localised brain damage (World Health Organisation, 1978), is without doubt a major challenge in health care, being the third most common cause of mortality in developed countries and the single greatest … Continue reading
Background Cervical pain from spondylosis or muscular problems is a very common symptom in the general adult population, estimated in a recent study to have a point prevalence of 4.9% and a global burden of 33.6 million disability-adjusted life years … Continue reading
Background One of the main issues facing a patient diagnosed as having had a first epileptic seizure without any sinister underlying lesion – often a young adult and otherwise well – is the driving ban. One can only be sympathetic … Continue reading
Introduction For this edition of the Neurology Online Journal Club I wanted to review not one but a series of papers to address a specific issue, namely predicting the risk of seizure recurrence after a single seizure and predicting how … Continue reading
Many of the journals discussed assume a knowledge of statistics. In fact, it is often the statistics that are the crucial issue in a critical review of a research study. And paradoxically it seems that the further we move from the more … Continue reading
Scientific Review For this paper, I decided to complete two complementary reviews. The Journal Club General Reader Review can be considered a background and a summary for this scientific review. Background It has been suggested for some time that, for a … Continue reading
Review for General Readers For this paper, I decided to complete two complementary reviews. This one for general readers can be considered a background and a summary for the Journal Club Scientific Review. Background For some time there has been a … Continue reading
