Category Archives: Stroke

Mechanical Thrombectomy for Ischaemic Stroke

  Introduction Stroke is the most common cause of disability in Western Countries, and its lifetime risk is 1 in 6 for men and 1 in 5 for women. While managing acute stroke patients in hyperacute stroke units overall has … Continue reading

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Comparison of New Oral Anticoagulants (NOACs) with Warfarin

Background Ischaemic stroke is typically either thrombotic (clotting within a cerebral vessel) or embolic (passage of clot material from a more proximal vessel to become lodged in a cerebral vessel). A proportion of embolic stroke events will arise from arterial … Continue reading

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Journal Club Review: “Cerebral Amyloid Angiopathy with and without Haemorrhage

Background Sporadic cerebral amyloid angiopathy (CAA) is the most common cause of lobar intracranial haemorrhage, which in itself accounts for about 5-10% of all strokes. Amyloid deposition in small arteries of the cerebrum leads to friability and haemorrhage. There are also … Continue reading

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Journal Club Review “Certainty of Stroke Diagnosis: Incremental Benefit with CT Perfusion over Non-Contrast CT and CT Angiography”

Background The accompanying primer,  Thrombolysis for Stroke and role of CT perfusion Imaging, describes the difficulties and potential shortcomings of thrombolysis for acute stroke and the way that CT perfusion may improve patient selection for thrombolysis. This paper, by Hopyat … Continue reading

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Primer on Thrombolysis for Stroke and Role of CT Perfusion Imaging

Stroke, defined as a sudden vascular event resulting in localised brain damage (World Health Organisation, 1978), is without doubt a major challenge in health care, being the third most common cause of mortality in developed countries and the single greatest … Continue reading

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