Tag Archives: Autoimmune

Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis

Recent studies indicate that higher strength disease modifying therapies (DMTs) may slow disability progression in secondary progressive multiple sclerosis (MS), as well as reduce the number of relapses. There have also been trials in primary progressive MS but these, most … Continue reading

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Thymectomy for Myasthenia Gravis

  Introduction While thymectomy has long been considered an option to treat myasthenia even if there is simply thymic tissue present rather than thymoma or thymic carcinoma, it has been uncertain how much benefit is achieved by undergoing this major … Continue reading

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Anti K+ Channel Antibodies in Neuromyotonia

Background At this Journal Club it was decided to review a historical paper on the pathophysiology underlying autoimmune neuromyotonia. The paper, “Autoantibodies Detected to Expressed K+ Channels Are Implicated in Neuromyotonia”, from Annals of Neurology (1997, 41:238-246), used a novel … Continue reading

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