Category Archives: Primer Posts for General Readers

Disease Modifying Therapies in Multiple Sclerosis: Background for General Readers

Multiple sclerosis (MS) is a presumed autoimmune condition of demyelination and often inflammation of the central nervous system. Its evolution is very variable; some patients suffer episodes lasting weeks to months with complete or near complete recovery in between, and … Continue reading

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Primer on Thrombolysis for Stroke and Role of CT Perfusion Imaging

Stroke, defined as a sudden vascular event resulting in localised brain damage (World Health Organisation, 1978), is without doubt a major challenge in health care, being the third most common cause of mortality in developed countries and the single greatest … Continue reading

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Primer on Statistics for Non-Statisticians

Many of the journals discussed assume a knowledge of statistics. In fact, it is often the statistics that are the crucial issue in a critical review of a research study. And paradoxically it seems that the further we move from the more … Continue reading

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Primer on Critical Illness Myopathy for General Readers

Neurology in Critical Care Despite the fact that Critical Care and Neurology are separately relatively “glamorous” medical disciplines, neurological diseases in the critical illness setting receive relatively little attention. However, if one is in the business of intervening to make … Continue reading

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Primer on Parkinson’s Disease for General Readers

Pathology Parkinson’s Disease (PD) is a relatively common condition affecting around 1% of all individuals aged over 60, and increasing towards 5% of those over 80. It is characterised by neurodegeneration, a “wearing out” of certain groups of nerve cells … Continue reading

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