Tag Archives: L-DOPA

Double-Blind Double-Dummy Randomised Study of Continuous Intrajejunal infusion of Levodopa-Carbidopa Intestinal Gel in Advanced Parkinson’s Disease

Background Levodopa, a pro-drug of dopamine, has been used successfully to treat symptoms of Parkinson’s disease for fifty years and remains the mainstay of medical management. However after years of treatment, with increasing loss of dopaminergic presynaptic terminals, symptomatic control … Continue reading

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Journal Club Review: A Double-Blind, Delayed-Start Trial of Rasagiline in Parkinson’s Disease

Summary for General Readers Given it was first introduced to treat Parkinson’s disease in the 1960’s (see the accompanying background information on Parkinson’s disease for general readers), it is surprising that it was not until four decades later that a major … Continue reading

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